rac-tilidine
Also known as ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate, rac-ethyl (1*,2*)-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate, (±)-tilidine, tilidine racemate
Tilidine, sold under the brand-name Valoron among others, is a synthetic opioid analgesic, used mainly in Belgium, Bulgaria, Germany, Albania, Luxembourg, and South Africa for the treatment of moderate to severe pain, both acute and chronic. Its onset of pain relief after oral administration is about 10-15 minutes and peak relief from pain occurs about 25-50 minutes after administration.
Chemical data
- Formula
- C17H23NO2
- Molecular weight
- 273.37 g/mol
- IUPAC name
- ethyl (2R)-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
- SMILES
- CCOC(=O)C1(CCC=C[C@H]1N(C)C)C2=CC=CC=C2
- InChIKey
- WDEFBBTXULIOBB-LDCVWXEPSA-N
- XLogP
- 3.1
- Polar surface area
- 29.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
~6 min read
Article
8 sectionsContents
- Medical uses
- Adverse effects
- Physicochemistry
- Pharmacology
- Pharmacokinetics
- Synthesis
- References
- External links
Tilidine, sold under the brand-name Valoron among others, is a synthetic opioid analgesic, used mainly in Belgium, Bulgaria, Germany, Albania, Luxembourg, and South Africa for the treatment of moderate to severe pain, both acute and chronic. Its onset of pain relief after oral administration is about 10-15 minutes and peak relief from pain occurs about 25-50 minutes after administration.
==Medical uses== thumb|left|Tilidine