RAP1GAP2
Sign in to saveAlso known as GARNL4, RAP1GA3, RAP1 GTPase activating protein 2
RAP1 GTPase activating protein 2 is a protein in humans that is encoded by the RAP1GAP2 gene.
Gene data
RAP1GAP2- Name
- RAP1 GTPase activating protein 2
- Type
- protein-coding
- Position
- 2,755,705–3,037,741 (+)
- Aliases
- GARNL4, RAP1GA3
- Ensembl
- ENSG00000132359
- RefSeq RNA
- NM_001100398.2, NM_001330058.2, NM_001411048.1, NM_001411049.1, NM_001437988.1
- RefSeq protein
- NP_001093868.1, NP_001316987.1, NP_001397977.1, NP_001397978.1, NP_001424917.1
This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
RAP1 GTPase activating protein 2
- Symbol
- RAP1GAP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:2,755,629-3,037,741
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 56695
- exact match
- identifiers.org/ncbigene/23108
- genomic end
- 3037741
- genomic start
- 2680350
- cytogenetic location
- 17p13.3
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
RAP1 GTPase activating protein 2 is a protein in humans that is encoded by the RAP1GAP2 gene.
This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].