Relaxin

Also known as IPR022421

Relaxin is a protein hormone of about 6000 Da, first described in 1926 by Frederick Hisaw.

Key facts

Protein.Name: Relaxin 3
Protein.image: relaxin.png
Protein.HGNCid: 17135
Protein.Symbol: RLN3
Protein.AltSymbols: ZINS4, RXN3, H3
Protein.EntrezGene: 117579
Protein.OMIM: 606855
Protein.RefSeq: NM_080864
Protein.UniProt: Q8WXF3
Protein.Chromosome: 19
Protein.Arm: p
Protein.Band: 13.3
Protein.LocusSupplementaryData: -q12

~9 min read

Article

16 sections

Contents

Synthesis
Structure
Function in humans
Reproduction
Cardiovascular function
Function in other animals
Reproduction
Cardiovascular function
Receptors
Disorders
Pregnancy
Pharmacological targets
Evolution
See also
References
External links

Relaxin is a protein hormone of about 6000 Da, first described in 1926 by Frederick Hisaw.

The relaxin family peptide hormones belong to the insulin superfamily and consists of seven peptides of high structural but low sequence similarity; relaxin-1 (RLN1), 2 (RLN2) and 3 (RLN3), and the insulin-like (INSL) peptides, INSL3, INSL4, INSL5 and INSL6. The functions of relaxin-3, INSL4, INSL5, and INSL6 remain uncharacterised.