RICTOR
Sign in to saveAlso known as AVO3, PIA, hAVO3, RPTOR independent companion of MTOR complex 2
Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene.
Gene data
RICTOR- Name
- RPTOR independent companion of MTOR complex 2
- Type
- protein-coding
- Aliases
- AVO3, PIA, hAVO3
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008].
via MyGene.info
Gene · Ensembl
RPTOR independent companion of MTOR complex 2
- Symbol
- RICTOR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:38,937,920-39,074,544
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 34317
- exact match
- identifiers.org/ncbigene/253260
- genomic end
- 39074399
- genomic start
- 38937920
- cytogenetic location
- 5p13.1
via Wikidata · CC0
~5 min read
Article
10 sectionsContents
- Structure
- Function
- Regulation
- Degradation
- Interactions
- Clinical relevance
- Cancer
- See also
- References
- Further reading
Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene.
RICTOR and mTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.