mechanistic target of rapamycin kinase

Also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2, serine/threonine-protein kinase mTOR, rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2, mechanistic target of rapamycin (serine/threonine kinase), Mechanistic target of rapamycin

The mechanistic target of rapamycin (mTOR), also known as mammalian target of rapamycin is a serine-threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. It belongs to the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is evolutionarily conserved across eukaryotes. It also promotes the activation of insulin receptors and insulin-like growth factor 1 receptors.