TXLNA
Sign in to saveAlso known as IL14, TXLN, IL-14, taxilin alpha
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene.
Gene data
TXLNA- Name
- taxilin alpha
- Type
- protein-coding
- Aliases
- IL-14, IL14, TXLN
Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis. Predicted to act upstream of or within B cell activation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
taxilin alpha
- Symbol
- TXLNA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:32,178,097-32,198,299
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 14062
- exact match
- identifiers.org/ncbigene/200081
- genomic end
- 32663886
- genomic start
- 32179675
- cytogenetic location
- 1p35.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Gene
- References
- External links
- Further reading
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene.
Interleukin-14 is a cytokine that controls the growth and proliferation of both normal and cancerous B cells. This molecule was also recently designated taxilin. IL-14 induces B-cell proliferation, inhibits antibody secretion, and expands selected B-cell subgroups. This interleukin is produced mainly by T cells and certain malignant B cells.