IL11
Sign in to saveAlso known as AGIF, IL-11, interleukin 11
protein-coding gene in the species Homo sapiens
Gene data
IL11- Name
- interleukin 11
- Type
- protein-coding
- Position
- 55,364,382–55,370,463 (−)
- Aliases
- AGIF, IL-11
- Ensembl
- ENSG00000095752
- RefSeq RNA
- NM_000641.4, NM_001267718.2
- RefSeq protein
- NP_000632.1, NP_001254647.1
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interleukin 11
- Symbol
- IL11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:55,364,382-55,370,463
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Human IL-11 crystal structure.png
Show 5 more facts
- HomoloGene ID
- 535
- exact match
- identifiers.org/ncbigene/3589
- genomic start
- 55364382
- genomic end
- 55881831
- cytogenetic location
- 19q13.42
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