Interleukin 1-alpha
Sign in to saveAlso known as IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α
protein-coding gene in the species Homo sapiens
Gene data
IL1A- Name
- interleukin 1 alpha
- Type
- protein-coding
- Position
- 112,773,916–112,784,500 (−)
- Aliases
- IL-1 alpha, IL-1A, IL1, IL1-ALPHA, IL1F1
- Ensembl
- ENSG00000115008
- RefSeq RNA
- NM_000575.5, NM_001371554.1
- RefSeq protein
- NP_000566.3, NP_001358483.1
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interleukin 1 alpha
- Symbol
- IL1A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:112,773,916-112,784,500
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 2ILA.png
Show 8 more facts
- HomoloGene ID
- 480
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3552
- genomic end
- 112784493
- genomic start
- 112773925
- chromosome
- human chromosome 2
- cytogenetic location
- 2q14.1
- expressed in
- islet of Langerhans
Sources (4)
via Wikidata · CC0