IL33

Also known as C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV, Interleukin 33, IL-33, IL-1F11

protein-coding gene in the species Homo sapiens

Gene data

IL33

Name: interleukin 33
Type: protein-coding
Position: 6,215,136–6,257,983 (+)
Aliases: C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV
Ensembl: ENSG00000137033
RefSeq RNA: NM_001199640.2, NM_001199641.2, NM_001314044.2, NM_001314045.2, NM_001314046.2
RefSeq protein: NP_001186569.1, NP_001186570.1, NP_001300973.1, NP_001300974.1, NP_001300975.1

The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].