C-C motif chemokine ligand 19
Also known as Macrophage inflammatory protein 3 beta, small-inducible cytokine A19, small inducible cytokine subfamily A (Cys-Cys), member 19, CC chemokine ligand 19, EBI1 ligand chemokine, CK beta-11, exodus-3, beta chemokine exodus-3
Chemokine (C-C motif) ligand 19 (CCL19) is a protein that in humans is encoded by the CCL19 gene.
Clinical Trials
1 registered- PHASE2UNKNOWNInterleukin-7 and Chemokine (C-C Motif) Ligand 19-expressing CD19-CAR-T for Refractory/Relapsed B Cell Lymphoma.Wenbin Qian · NCT03929107
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Chemokine (C-C motif) ligand 19 (CCL19) is a protein that in humans is encoded by the CCL19 gene.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7.