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EntityQ182517· pop 18· linked from 66 articles

Also known as CA 19-9, carbohydrate antigen 19-9, cancer antigen 19-9, sialylated Lewis (a) antigen, Carbohydrate antigen 19-9, CA-19-9 Antigen, alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc, NeuAcalpha2,3Galbeta1-3[Fucalpha1-4]GlcNAc

Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-LewisA, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer.

Research

9,811 papers

via PubMed

Wikidata facts

Mass
820.296
Show 3 more facts
isomeric SMILES
C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H](OC([C@@H]([C@H]2O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O[C@@]4(C[C@@H]([C@H]([C@@H](O4)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)NC(=O)C)O)CO)O)O)O
canonical SMILES
CC1C(C(C(C(O1)OC2C(OC(C(C2OC3C(C(C(C(O3)CO)O)OC4(CC(C(C(O4)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)NC(=O)C)O)CO)O)O)O
chemical formula
C₃₁H₅₂N₂O₂₃
Sources (3)

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~2 min read

Article

8 sections
Contents
  • Structure
  • Clinical significance
  • Tumor marker
  • Limitations
  • History
  • See also
  • References
  • External links

Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-LewisA, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer.

==Structure== CA19-9 is the sialylated form of Lewis antigenA. It is a tetrasaccharide with the sequence Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAcβ.

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