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ProteinQ21151085· pop 7· linked from 360 articles

CEA cell adhesion molecule 8

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Also known as carcinoembryonic antigen CGM6, non-specific cross-reacting antigen NCA-95, CD67 antigen, carcinoembryonic antigen-related cell adhesion molecule 8, carcinoembryonic antigen related cell adhesion molecule 8, carcinoembryonic antigen gene family member 6, CEACAM8

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), is a member of the carcinoembryonic antigen (CEA) gene family. Its main function is cell adhesion, cell migration, and pathogen binding.

In the Vinony graph

Vinony's link graph records 360 inbound references to CEA cell adhesion molecule 8, and connects out to PubMed, Ensembl genome database project and CD1.

It is catalogued under topics including Clusters of differentiation and Genes on human chromosome 19.

Vinony links it to 6 Wikipedia language editions.

Protein · UniProt

Cell adhesion molecule CEACAM8

Gene
CEACAM8
Organism
Homo sapiens (Human)
Length
349 aa
Molecular mass
38,154 Da
Evidence
1: Evidence at protein level

Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:11590190, PubMed:2022629, PubMed:8776764). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:11590190, PubMed:2022629, PubMed:8776764). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764)

3D-structureCell adhesionCell membraneDisulfide bondGlycoproteinGPI-anchorImmunoglobulin domainLipoprotein
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Swiss-Prot (reviewed) · via UniProt

Wikidata facts

Instance of
protein
Show 2 more facts
cell component
extracellular exosome
found in taxon
Homo sapiens
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Use
  • See also
  • References
  • Further reading
  • External links

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), is a member of the carcinoembryonic antigen (CEA) gene family. Its main function is cell adhesion, cell migration, and pathogen binding.

==Use== CEACAM8 is expressed exclusively on granulocytes and used as granulocyte marker.

Excerpted from Wikipedia’s “CEA cell adhesion molecule 8” article, available under the CC BY-SA 4.0 licence.

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