CEACAM1 protein
Sign in to saveAlso known as CEA cell adhesion molecule 1, antigen CD66, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), carcinoembryonic antigen related cell adhesion molecule 1, BGP-1, Biliary glycoprotein 1, CD66a antigen
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.
Protein · UniProt
CEACAM1 protein
- Gene
- CEACAM1
- Organism
- Homo sapiens (Human)
- Length
- 493 aa
- Molecular mass
- 53,343 Da
- Evidence
- 2: Evidence at transcript level
Swiss-Prot (reviewed) · via UniProt
Research
653 papers- Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by inducing CEACAM1 N153 fucosylation.Hepatology (Baltimore, Md.) · 2025
- Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2/S1PR3 axis in liver transplantation.The Journal of clinical investigation · 2023
- Glycan Conformation in the Heavily Glycosylated Protein, CEACAM1.ACS chemical biology · 2022
- CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma.Nature communications · 2025
- CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.Nature · 2015
via PubMed
Clinical Trials
1 registered- PHASE2TERMINATEDHigh-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell TransplantUniversity of Southampton · NCT00637767
Wikidata facts
- Instance of
- protein
Show 1 more fact
- found in taxon
- Homo sapiens
Sources (4)
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.
== Function ==
Excerpted from Wikipedia’s “CEACAM1 protein” article, available under the CC BY-SA 4.0 licence.