CTSD
Sign in to saveAlso known as CLN10, CPSD, HEL-S-130P, cathepsin D
protein-coding gene in the species Homo sapiens
Gene data
CTSD- Name
- cathepsin D
- Type
- protein-coding
- Aliases
- CLN10, CPSD, HEL-S-130P
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015].
via MyGene.info
Gene · Ensembl
cathepsin D
- Symbol
- CTSD
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:1,752,752-1,764,573
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CTSD PDB 1lya.png
Show 5 more facts
- HomoloGene ID
- 55616
- exact match
- identifiers.org/ncbigene/1509
- genomic start
- 1752752
- genomic end
- 1764573
- cytogenetic location
- 11p15.5
Sources (7)
via Wikidata · CC0