CTF1
Sign in to saveAlso known as cardiotrophin 1, CT-1, CT1
protein-coding gene in the species Homo sapiens
Gene data
CTF1- Name
- cardiotrophin 1
- Type
- protein-coding
- Position
- 30,896,614–30,903,547 (+)
- Aliases
- CT-1, CT1
- Ensembl
- ENSG00000150281
- RefSeq RNA
- NM_001142544.3, NM_001330.5, NR_165660.1, XM_011545759.3, XM_011545760.3
- RefSeq protein
- NP_001136016.1, NP_001321.1, XP_011544061.1, XP_011544062.1, XP_054235666.1
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Cytokine-cytokine receptor interaction - Homo sapiens (human)JAK-STAT signaling pathway - Homo sapiens (human)Cytokine Signaling in Immune systemImmune SystemSignaling by InterleukinsInterleukin-6 family signalingIL-6-type cytokine receptor ligand interactionsPhysiological and pathological hypertrophy of the heartMicroRNAs in cardiomyocyte hypertrophyRegulatory circuits of the STAT3 signaling pathway
via MyGene.info
Gene · Ensembl
cardiotrophin 1
- Symbol
- CTF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:30,896,607-30,903,547
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1016
- exact match
- identifiers.org/ncbigene/1489
- genomic end
- 30903547
- genomic start
- 30896614
- cytogenetic location
- 16p11.2
Sources (4)
via Wikidata · CC0
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