IL20
Sign in to saveAlso known as IL-20, IL10D, ZCYTO10, Interleukin 20
protein-coding gene in the species Homo sapiens
Gene data
IL20- Name
- interleukin 20
- Type
- protein-coding
- Position
- 206,865,623–206,869,223 (+)
- Aliases
- IL-20, IL10D, ZCYTO10
- Ensembl
- ENSG00000162891
- RefSeq RNA
- NM_001385165.1, NM_001385166.1, NM_001385167.1, NM_018724.4
- RefSeq protein
- NP_001372094.1, NP_001372095.1, NP_001372096.1, NP_061194.2
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
immune responsecytokine-mediated signaling pathwayosteoclast differentiationpositive regulation of tyrosine phosphorylation of STAT proteinpositive regulation of epidermal cell differentiationpositive regulation of keratinocyte differentiationregulation of inflammatory responsedendritic cell differentiation
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
interleukin 20
- Symbol
- IL20
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,865,621-206,869,223
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 10286
- exact match
- identifiers.org/ncbigene/50604
- genomic start
- 207038699
- genomic end
- 207042568
- cytogenetic location
- 1q32.1
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