interleukins
Sign in to saveAlso known as interleukin
Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins.
Research
463,586 papers- Key Interleukins in Inflammatory Bowel Disease-A Review of Recent Studies.International journal of molecular sciences · 2024
- The interleukins.Pediatric research · 1988
- Interleukins in Urine and Blood as Markers of Infection and as Risk Factors for Systemic Conditions.European urology focus · 2024
- New interleukins: are there any more?Current opinion in infectious diseases · 2003
- Pleural fluid interleukins for diagnosis of tuberculous pleural effusion: A systematic review and meta-analysis.Cytokine · 2022
via PubMed
~21 min read
Article
21 sectionsContents
- History and name
- Common families
- Interleukin 1
- Interleukin 2
- Interleukin 3
- Interleukin 4
- Interleukin 5
- Interleukin 6
- Interleukin 7
- Interleukin 8
- Interleukin 9
- Interleukin 10
- Interleukin 11
- Interleukin 12
- Interleukin 13
- Interleukin 15
- Interleukin 17
- In humans
- International nonproprietary names for analogues and derivatives
- References
- External links
Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins.
The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.