IL19
Sign in to saveAlso known as IL-10C, MDA1, NG.1, ZMDA1, Interleukin 19, IL-19
protein-coding gene in the species Homo sapiens
Gene data
IL19- Name
- interleukin 19
- Type
- protein-coding
- Position
- 206,770,764–206,842,981 (+)
- Aliases
- IL-10C, MDA1, NG.1, ZMDA1
- Ensembl
- ENSG00000142224
- RefSeq RNA
- NM_001369605.1, NM_001393490.1, NM_001393491.1, NM_013371.5, NM_153758.5
- RefSeq protein
- NP_001356534.1, NP_001380419.1, NP_001380420.1, NP_037503.2, NP_715639.2
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interleukin 19
- Symbol
- IL19
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,770,764-206,842,981
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- IL19 Crystal Structure.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/29949
- HomoloGene ID
- 17813
- genomic start
- 206770764
- genomic end
- 206842981
- cytogenetic location
- 1q32.1
via Wikidata · CC0