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GeneQ18033332· pop 5· linked from 12 articles

Also known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor interacting serine/threonine kinase 2

Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.

Gene data

RIPK2
Name
receptor interacting serine/threonine kinase 2
Type
protein-coding
Aliases
CARD3, CARDIAK, CCK, GIG30, RICK, RIP2

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

receptor interacting serine/threonine kinase 2

Symbol
RIPK2
Biotype
Protein coding
Organism
Homo sapiens
Location
8:89,757,733-89,791,847
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 6 more facts
cytogenetic location
8q21.3
HomoloGene ID
37856
genomic end
89791064
genomic start
89757806
Commons category
RIPK2
Sources (5)

via Wikidata · CC0

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Article

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Contents
  • Interactions
  • References
  • Further reading

Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-κB and inducer of apoptosis in response to various stimuli.

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