RIPK2
Sign in to saveAlso known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor interacting serine/threonine kinase 2
Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.
Gene data
RIPK2- Name
- receptor interacting serine/threonine kinase 2
- Type
- protein-coding
- Aliases
- CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
receptor interacting serine/threonine kinase 2
- Symbol
- RIPK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:89,757,733-89,791,847
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- cytogenetic location
- 8q21.3
- HomoloGene ID
- 37856
- exact match
- identifiers.org/ncbigene/8767
- genomic end
- 89791064
- genomic start
- 89757806
- Commons category
- RIPK2
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-κB and inducer of apoptosis in response to various stimuli.