rufloxacin

Chemical data

Formula

C17H18FN3O3S

Molecular weight

363.4 g/mol

IUPAC name

7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

SMILES

CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F

InChIKey

NJCJBUHJQLFDSW-UHFFFAOYSA-N

XLogP

-0.3

Polar surface area

89.4 Ų

H-bond donors

1

H-bond acceptors

8

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

Indications

bacterial disease

via ChEMBL · EBI

• Rufloxacin-induced photosensitization in yeast.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2007
• Comparison of single preoperative oral rufloxacin versus perioperative ciprofloxacin as prophylactic agents in transurethral surgery.Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica · 2000
• The in-vitro activity of two new quinolones: rufloxacin and MF 961.The Journal of antimicrobial chemotherapy · 1992
• Antibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis.The Cochrane database of systematic reviews · 2020
• Single-dose rufloxacin versus 3-day norfloxacin treatment of uncomplicated cystitis: clinical evaluation and pharmacodynamic considerations.Antimicrobial agents and chemotherapy · 1996

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

363.105

Has use

medication

via Wikidata · CC0