RUVBL2
Sign in to saveAlso known as ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B, CGI-46
RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.
Gene data
RUVBL2- Name
- RuvB like AAA ATPase 2
- Type
- protein-coding
- Position
- 48,993,562–49,015,983 (+)
- Aliases
- CGI-46, ECP-51, ECP51, INO80J, REPTIN, RVB2, TAP54-beta, TIH2, TIP48, TIP49B
- Ensembl
- ENSG00000183207
- RefSeq RNA
- NM_001321190.2, NM_001321191.1, NM_006666.3, NR_135578.2
- RefSeq protein
- NP_001308119.1, NP_001308120.1, NP_006657.1
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RuvB like AAA ATPase 2
- Symbol
- RUVBL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:48,993,476-49,017,868
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein RUVBL2 PDB 2cqa.png
Show 5 more facts
- HomoloGene ID
- 4856
- exact match
- identifiers.org/ncbigene/10856
- genomic start
- 48993562
- genomic end
- 49015970
- cytogenetic location
- 19q13.33
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.
== Function ==