sarcopenia
Sign in to saveSarcopenia (ICD-10-CM code M62.84) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors. The muscle loss is related to changes in muscle synthesis signalling pathways. It is distinct from cachexia, in which muscle is degraded through cytokine-mediated degradation, although the two conditions may coexist. Sarcopenia is considered a component of frailty syndrome. Sarcopenia can lead to reduce
Key facts
- Medical condition (new).name
- Sarcopenia
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- File:1025 Atrophy.png
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- Difference between a normal muscle and an atrophied muscle
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- GeriatricsRheumatology
via Wikipedia infobox
Research
30,199 papers- Epidemiology of sarcopenia: Prevalence, risk factors, and consequences.Metabolism: clinical and experimental · 2023
- A Review of Sarcopenia Pathophysiology, Diagnosis, Treatment and Future Direction.Journal of Korean medical science · 2022
- Sarcopenia in youth.Metabolism: clinical and experimental · 2023
- Sarcopenia: A Contemporary Health Problem among Older Adult Populations.Nutrients · 2020
- Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies.Molecular aspects of medicine · 2024
via PubMed
Clinical Trials
1,316 registered- NARECRUITINGEffectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)Fondazione Don Carlo Gnocchi Onlus · NCT07599306
- COMPLETEDPrevalence of Sarcopenia and Sarcopenic Obesity in Older AdultsGoztepe Training and Research Hospital · NCT04122638
- NARECRUITINGEffects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized TrialGaziosmanpasa Research and Education Hospital · NCT07575958
- NAACTIVE_NOT_RECRUITINGAquatic High-Intensity Interval Training for Parkinson's DiseasePardis Specialized Wellness Institute · NCT07264114
- PHASE3COMPLETEDCarnitine Supplementation and Skeletal Muscle FunctionGdansk University of Physical Education and Sport · NCT02692235
- NARECRUITINGSilkworm Pupa Powder Improves Dementia.Zhejiang Provincial Tongde Hospital · NCT06898476
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Article
17 sectionsContents
- Signs and symptoms
- Causes
- Pathophysiology
- Diagnosis
- Biomarkers
- Management
- Exercise
- Medication
- Nutrition
- Supplements
- Epidemiology
- Public health impact
- Etymology
- Research directions
- See also
- References
- Further reading
Sarcopenia (ICD-10-CM code M62.84) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors. The muscle loss is related to changes in muscle synthesis signalling pathways. It is distinct from cachexia, in which muscle is degraded through cytokine-mediated degradation, although the two conditions may coexist. Sarcopenia is considered a component of frailty syndrome. Sarcopenia can lead to reduced quality of life, falls, fracture, and disability.
Sarcopenia is a factor in changing body composition. When associated with aging populations, certain muscle regions are expected to be affected first, specifically the anterior thigh and abdominal muscles. In population studies, body mass index (BMI) is seen to decrease in aging populations while bioelectrical impedance analysis (BIA) shows body fat proportion rising.