SEC62
Sign in to saveAlso known as Dtrp1, HTP1, TLOC1, TP-1, SEC62 homolog, preprotein translocation factor
Translocation protein SEC62 is a protein that in humans is encoded by the SEC62 gene.
Gene data
SEC62- Name
- SEC62 preprotein translocation factor
- Type
- protein-coding
- Position
- 169,966,635–169,998,373 (+)
- Aliases
- Dtrp1, HTP1, TLOC1, TP-1
- Ensembl
- ENSG00000008952
- RefSeq RNA
- NM_003262.4, XM_011513114.4, XM_047448819.1, XM_054347705.1, XM_054347706.1
- RefSeq protein
- NP_003253.1, XP_011511416.1, XP_047304775.1, XP_054203680.1, XP_054203681.1
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SEC62 preprotein translocation factor
- Symbol
- SEC62
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:169,966,635-169,998,373
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2449
- exact match
- identifiers.org/ncbigene/7095
- genomic end
- 169716161
- genomic start
- 169684423
- cytogenetic location
- 3q26.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Translocation protein SEC62 is a protein that in humans is encoded by the SEC62 gene.
== Function ==