SINHCAF

Also known as C12orf14, TERA, L4, FAM60A, family with sequence similarity 60 member A, SIN3-HDAC complex associated factor

Protein FAM60A is a protein that in humans is encoded by the FAM60A gene. The expression of FAM60A gene is higher in KRAS mutant non-small cell lung cancer.

In the Vinony graph

Vinony's link graph records 2 inbound references to SINHCAF, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 12.

Vinony links it to 6 Wikipedia language editions.

Gene data

SINHCAF

Name: SIN3-HDAC complex associated factor
Type: protein-coding
Position: 31,280,423–31,327,058 (−)
Aliases: C12orf14, FAM60A, L4, TERA
Ensembl: ENSG00000139146
RefSeq RNA: NM_001135811.2, NM_001135812.2, NM_021238.3, XM_011520803.3, XM_017019762.3
RefSeq protein: NP_001129283.1, NP_001129284.1, NP_067061.1, XP_011519105.2, XP_016875251.1

Involved in negative regulation of cell migration. Part of Sin3 complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell migration negative regulation of cell migration negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of cell differentiation

Molecular function

protein binding

Cellular component

nucleus nucleus nucleus Sin3-type complex Sin3-type complex Sin3-type complex

via MyGene.info

Gene · Ensembl

SIN3-HDAC complex associated factor

Symbol: SINHCAF
Biotype: Protein coding
Organism: Homo sapiens
Location: 12:31,280,423-31,327,058
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 10494
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/58516
chromosome: human chromosome 12
genomic start: 31433518
genomic end: 31479992
cytogenetic location: 12p11.21
expressed in: appendix

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Protein FAM60A is a protein that in humans is encoded by the FAM60A gene. The expression of FAM60A gene is higher in KRAS mutant non-small cell lung cancer.

==References==

Excerpted from Wikipedia’s “SINHCAF” article, available under the CC BY-SA 4.0 licence.