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GeneQ18042933· pop 6· linked from 8 articles

SLURP1

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Also known as ANUP, ARS, ArsB, LY6LS, MDM, secreted LY6/PLAUR domain containing 1, LY6-MT

Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene. It exerts anti-inflammatory effects, acts as a tumor suppressor, and antagonizes nicotinic receptors.

Gene data

SLURP1
Name
secreted LY6/PLAUR domain containing 1
Type
protein-coding
Position
142,740,941–142,742,414 (−)
Aliases
ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM
Ensembl
ENSG00000126233
RefSeq RNA
NM_020427.3
RefSeq protein
NP_065160.1

The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

secreted LY6/PLAUR domain containing 1

Symbol
SLURP1
Biotype
Protein coding
Organism
Homo sapiens
Location
8:142,740,941-142,742,414
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 9 more facts
exact match
identifiers.org/ncbigene/57152
HomoloGene ID
10710
found in taxon
Homo sapiens
genomic end
142742406
genomic start
142740949
chromosome
human chromosome 8
cytogenetic location
8q24.3
genetic association
Mal de Meleda
expressed in
gums
Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Function
  • References
  • Further reading

Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene. It exerts anti-inflammatory effects, acts as a tumor suppressor, and antagonizes nicotinic receptors.

== Function ==

Excerpted from Wikipedia’s “SLURP1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0