SMTN
Sign in to saveAlso known as smoothelin
Smoothelin is a protein that in humans is encoded by the SMTN gene.
Gene data
SMTN- Name
- smoothelin
- Type
- protein-coding
- Position
- 31,064,105–31,104,757 (+)
- Ensembl
- ENSG00000183963
- RefSeq RNA
- NM_001207017.1, NM_001207018.2, NM_001382638.1, NM_001382639.1, NM_001382640.1
- RefSeq protein
- NP_001193946.1, NP_001193947.1, NP_001369567.1, NP_001369568.1, NP_001369569.1
This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011].
Gene Ontology
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
smoothelin
- Symbol
- SMTN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:31,064,105-31,104,757
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SMTN PDB 2d87.png
Show 8 more facts
- HomoloGene ID
- 8482
- found in taxon
- Homo sapiens
- cytogenetic location
- 22q12.2
- exact match
- identifiers.org/ncbigene/6525
- genomic end
- 31500743
- genomic start
- 31460091
- chromosome
- human chromosome 22
- expressed in
- right coronary artery
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Smoothelin is a protein that in humans is encoded by the SMTN gene.
This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in three transcript variants.
Excerpted from Wikipedia’s “SMTN” article, available under the CC BY-SA 4.0 licence.