myofibroblast
Sign in to saveAlso known as myofibroblasts, myofibroblast cell
A myofibroblast is a cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell.
Key facts
- Cell.Name
- Myofibroblast
- Cell.Latin
- myofibroblastus
- Cell.Image
- Testicle-histology-boar.jpg
- Cell.Caption
- Histological section through testicular parenchyma of a boar. 1 Lumen of tubulus seminiferus contortus, 2 spermatids, 3 spermatocytes, 4 spermatogonia, 5 Sertoli cell, 6 Myofibroblasts, 7 Leydig cells, 8 capillaries
via Wikipedia infobox
Research
24,218 papers- Fibroblast and myofibroblast activation in normal tissue repair and fibrosis.Nature reviews. Molecular cell biology · 2024
- PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice.The Journal of clinical investigation · 2025
- The role of the macrophage-to-myofibroblast transition in renal fibrosis.Frontiers in immunology · 2022
- Advances in macrophage-myofibroblast transformation in fibrotic diseases.Frontiers in immunology · 2024
- Macrophage-to-myofibroblast transition and its role in cardiac fibrosis.International immunopharmacology · 2025
via PubMed
~5 min read
Encyclopedic overview
9 sectionsContents
- Structure
- Location
- Markers
- Development
- Function
- Wound healing
- See also
- References
- External links
A myofibroblast is a cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell.
== Structure == Myofibroblasts are contractile web-like fusiform cells that are identifiable by their expression of α-smooth muscle actin within their cytoplasmic stress fibers.
Excerpted from Wikipedia’s “myofibroblast” article, available under the CC BY-SA 4.0 licence.