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GeneQ18036498· pop 5· linked from 35 articles

ITGA11

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Also known as HsT18964, integrin subunit alpha 11

protein-coding gene in the species Homo sapiens

Gene data

ITGA11

Name: integrin subunit alpha 11
Type: protein-coding
Position: 68,296,532–68,432,216 (−)
Aliases: HsT18964
Ensembl: ENSG00000137809
RefSeq RNA: NM_001004439.2, NM_012211.3, XM_005254228.4, XM_011521363.3
RefSeq protein: NP_001004439.1, XP_005254285.1, XP_011519665.1

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008].

Pathways

PI3K-Akt signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)ECM-receptor interaction - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Human papillomavirus infection - Homo sapiens (human)Hypertrophic cardiomyopathy - Homo sapiens (human)Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)Dilated cardiomyopathy - Homo sapiens (human)Extracellular matrix organization Extracellular matrix organization

via MyGene.info

Gene · Ensembl

integrin subunit alpha 11

Symbol: ITGA11
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:68,296,532-68,432,216
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 8151
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/22801
genomic end: 68432163
genomic start: 68296532
chromosome: human chromosome 15
cytogenetic location: 15q23
expressed in: popliteal artery

Sources (5)

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