ITGA7

Name

integrin subunit alpha 7

Type

protein-coding

Position

55,684,568–55,716,404 (−)

Ensembl

ENSG00000135424

RefSeq RNA

NM_001144996.2, NM_001144997.2, NM_001367993.1, NM_001367994.1, NM_001374465.1

RefSeq protein

NP_001138468.1, NP_001138469.1, NP_001354922.1, NP_001354923.1, NP_001361394.1

The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009].

via MyGene.info

Gene · Ensembl

integrin subunit alpha 7

Symbol

ITGA7

Biotype

Protein coding

Organism

Homo sapiens

Location

12:55,679,139-55,716,404

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0