Integrin subunit alpha X

Also known as myeloid membrane antigen, alpha subunit, leukocyte surface antigen p150,95, alpha subunit, leukocyte adhesion glycoprotein p150,95 alpha chain, CD11 antigen-like family member C, leukocyte adhesion receptor p150,95, complement component 3 receptor 4 subunit, integrin alpha X, p150 95 integrin alpha chain

mammalian protein found in Homo sapiens

Protein · UniProt

Integrin alpha-X

Gene: ITGAX
Organism: Homo sapiens (Human)
Length: 1,163 aa
Molecular mass: 127,829 Da
Evidence: 1: Evidence at protein level

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Functions as a receptor of the erythrocyte-specific adhesion molecule ICAM4 and mediates erythrophagocytosis (PubMed:16985175)

3D-structureCalciumCell adhesionCell membraneDirect protein sequencingDisulfide bondGlycoproteinIntegrin

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Swiss-Prot (reviewed) · via UniProt