integrin subunit alpha 2

Also known as integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), VLA-2 subunit alpha, GPIa, platelet antigen Br, human platelet alloantigen system 5, collagen receptor, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 subunit

mammalian protein found in Homo sapiens

Protein · UniProt

Integrin alpha-2

Gene: ITGA2
Organism: Homo sapiens (Human)
Length: 1,181 aa
Molecular mass: 129,296 Da
Evidence: 1: Evidence at protein level

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix

3D-structureCalciumCell adhesionDirect protein sequencingDisulfide bondGlycoproteinHost cell receptor for virus entryHost-virus interaction

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Swiss-Prot (reviewed) · via UniProt