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desmoplasia

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Also known as desmoplastic reaction

thumb|Desmoplastic small round cell tumour, with desmoplasia surrounding nests of cancer cells. In medicine, desmoplasia is the growth of fibrous connective tissue. It is also called a desmoplastic reaction to emphasize that it is secondary to an insult. Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor, or scar tissue (adhesions) within the abdomen after abdominal surgery.

In the Vinony graph

Within Vinony's link graph, desmoplasia is referenced by 26 other articles, and connects out to neoplasm, atrophy and stroma.

It is catalogued under the topic Types of neoplasia.

Its subject is documented across 6 Wikipedia language editions.

Wikidata facts

Subclass of
fibrosis
Show 1 more fact
Commons category
Desmoplasia
Sources (2)

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~8 min read

Encyclopedic overview

14 sections
Contents
  • Terminology
  • Normal tissue structure and wound response
  • Cancer
  • Growth factors for vascularization, migration, degradation, proliferation
  • Underlying mechanisms
  • Characteristics of desmoplastic stromal response
  • Differentiation of scars
  • Examples
  • Benign condition examples
  • Malignant condition examples
  • Prostate cancer
  • Breast cancer
  • See also
  • References

thumb|Desmoplastic small round cell tumour, with desmoplasia surrounding nests of cancer cells. In medicine, desmoplasia is the growth of fibrous connective tissue. It is also called a desmoplastic reaction to emphasize that it is secondary to an insult. Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor, or scar tissue (adhesions) within the abdomen after abdominal surgery.

Desmoplasia is usually only associated with malignant neoplasms, which can evoke a fibrotic response invading healthy tissue. Invasive ductal carcinomas of the breast often have a stellate appearance caused by desmoplastic formations.

Excerpted from Wikipedia’s “desmoplasia” article, available under the CC BY-SA 4.0 licence.

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