SNF8
Sign in to saveAlso known as Dot3, EAP30, VPS22, SNF8, ESCRT-II complex subunit, SNF8 subunit of ESCRT-II
Vacuolar-sorting protein SNF8 is a protein that in humans is encoded by the SNF8 gene. It is a part of ESCRT-II complex.
Gene data
SNF8- Name
- SNF8 subunit of ESCRT-II
- Type
- protein-coding
- Aliases
- DEE115, Dot3, EAP30, NEDOA, VPS22
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].
via MyGene.info
Gene · Ensembl
SNF8 subunit of ESCRT-II
- Symbol
- SNF8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,928,972-48,944,842
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein VPS25 PDB 2ZME.png
Show 5 more facts
- HomoloGene ID
- 5239
- exact match
- identifiers.org/ncbigene/11267
- genomic end
- 48944842
- genomic start
- 47006678
- cytogenetic location
- 17q21.32
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Vacuolar-sorting protein SNF8 is a protein that in humans is encoded by the SNF8 gene. It is a part of ESCRT-II complex.
==References==