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GeneQ18033243· pop 5· linked from 23 articles

Also known as ATG24B, sorting nexin 4

Sorting nexin-4 is a protein that in humans is encoded by the SNX4 gene.

Gene data

SNX4
Name
sorting nexin 4
Type
protein-coding
Aliases
ATG24B

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012].

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Gene · Ensembl

sorting nexin 4

Symbol
SNX4
Biotype
Protein coding
Organism
Homo sapiens
Location
3:125,446,642-125,520,233
Strand
Reverse (−)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
36143
genomic end
125520202
genomic start
125446650
cytogenetic location
3q21.2
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Sorting nexin-4 is a protein that in humans is encoded by the SNX4 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.

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