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Somatopause

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Somatopause is the progressive decline in the levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), hormones of the hypothalamic–pituitary–somatotropic axis (HPS axis), with age. Secretion of GH may only be 60% of that of a young adult by age 70 years. Somatopause results in changes in the body, such as body composition changes like a decrease in lean body mass. Estrogens and progesterone may oppose somatopause by increasing GH and IGF-1 levels.

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Within Vinony's link graph, Somatopause is referenced by 3 other articles, and connects out to biology, International Standard Book Number and hormone.

It sits within the topics Developmental stages and Endocrine system.

Its subject is documented across 5 Wikipedia language editions.

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Somatopause is the progressive decline in the levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), hormones of the hypothalamic–pituitary–somatotropic axis (HPS axis), with age. Secretion of GH may only be 60% of that of a young adult by age 70 years. Somatopause results in changes in the body, such as body composition changes like a decrease in lean body mass. Estrogens and progesterone may oppose somatopause by increasing GH and IGF-1 levels.

==References==

Excerpted from Wikipedia’s “Somatopause” article, available under the CC BY-SA 4.0 licence.

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