IGF1
Sign in to saveAlso known as IGF-I, IGF1A, IGFI, MGF, insulin like growth factor 1, IGF
protein-coding gene in the species Homo sapiens
Gene data
IGF1- Name
- insulin like growth factor 1
- Type
- protein-coding
- Position
- 102,395,874–102,481,744 (−)
- Aliases
- IGF, IGF-I, IGFI, MGF
- Ensembl
- ENSG00000017427
- RefSeq RNA
- NM_000618.5, NM_001111283.3, NM_001111284.2, NM_001111285.3, NM_001414005.1
- RefSeq protein
- NP_000609.1, NP_001104753.1, NP_001104754.1, NP_001104755.1, NP_001400934.1
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
insulin like growth factor 1
- Symbol
- IGF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:102,395,874-102,481,857
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein IGF1 PDB 1bqt.png
Show 6 more facts
- HomoloGene ID
- 515
- exact match
- identifiers.org/ncbigene/3479
- genomic end
- 102481744
- genomic start
- 102395874
- cytogenetic location
- 12q23.2
- Commons category
- Insulin-like growth factor I
via Wikidata · CC0