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sphingolipids
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sphingolipids

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Also known as sphingolipid

thumb|500px|class=skin-invert|General structures of sphingolipids

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Sphingolipids
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Article

12 sections
Contents
  • Structure
  • Types
  • Mammalian sphingolipid metabolism
  • Functions of mammalian sphingolipids
  • Other sphingolipids
  • Yeast sphingolipids
  • Plant sphingolipids
  • Disorders
  • Additional images
  • See also
  • References
  • External links

thumb|500px|class=skin-invert|General structures of sphingolipids

Sphingolipids are a class of lipids containing a backbone of sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine. They were discovered in brain extracts in the 1870s and were named after the mythological sphinx because of their enigmatic nature. These compounds play important roles in signal transduction and cell recognition. Sphingolipidoses, or disorders of sphingolipid metabolism, have particular impact on neural tissue. A sphingolipid with a terminal hydroxyl group is a ceramide. Other common groups bonded to the terminal oxygen atom include phosphocholine, yielding a sphingomyelin, and various sugar monomers or dimers, yielding cerebrosides and globosides, respectively. Cerebrosides and globosides are collectively known as glycosphingolipids.

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