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GeneQ18031721· pop 7· linked from 11 articles

Also known as LARP3, La, La/SSB, Sjogren syndrome antigen B, small RNA binding exonuclease protection factor La

protein-coding gene in the species Homo sapiens

Gene data

SSB
Name
small RNA binding exonuclease protection factor La
Type
protein-coding
Aliases
LARP3, La, La/SSB

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014].

via MyGene.info

Gene · Ensembl

small RNA binding exonuclease protection factor La

Symbol
SSB
Biotype
Protein coding
Organism
Homo sapiens
Location
2:169,791,933-169,812,091
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein SSB PDB 1owx.png
Show 5 more facts
HomoloGene ID
2366
genomic end
170668574
genomic start
170648443
cytogenetic location
2q31.1
Sources (4)

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