Structure via PubChem · Public domain (PubChem)
sulfalene
Sign in to saveAlso known as Kelfizina, Solfametopirazina, Sulfaleno, Sulfalenum, Sulfametopyrazine
Sulfalene (INN, USAN) or sulfametopyrazine (BAN) is a long-acting sulfonamide antibacterial used for the treatment of chronic bronchitis, urinary tract infections and malaria. As of 2014 there were only two countries in which it is currently still marketed: Thailand and Ireland.
Chemical data
- Formula
- C11H12N4O3S
- Molecular weight
- 280.31 g/mol
- IUPAC name
- 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Admin. routes
- oral
- Indications
- malaria, bacterial disease
via ChEMBL · EBI
Research
195 papers- [Sulfalene].Fel'dsher i akusherka · 1978
- [Sulfalene].Farmatsiia · 1977
- Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial.Parasites & vectors · 2024
- Efficacy of a Single Oral Dose of Artesunate plus Sulfalene-Pyrimethamineversus Praziquantel in the Treatment of Schistosoma mansoni in Kenyan Children: An Open-Label, Randomized, Exploratory Trial.The American journal of tropical medicine and hygiene · 2024
- The influence of acetylator phenotype on the response to sulfalene in individuals with chloroquine-resistant falciparum malaria.The American journal of tropical medicine and hygiene · 1978
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 280.063011
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₁H₁₂N₄O₃S
- canonical SMILES
- COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)N
- defined daily dose
- 0.1
- subject has role
- antimalarial
- Commons category
- Sulfalene
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Sulfalene (INN, USAN) or sulfametopyrazine (BAN) is a long-acting sulfonamide antibacterial used for the treatment of chronic bronchitis, urinary tract infections and malaria. As of 2014 there were only two countries in which it is currently still marketed: Thailand and Ireland.
It was discovered by researchers at Farmitalia and first published in 1960 and was marketed as Kelfizina.
Excerpted from Wikipedia’s “sulfalene” article, available under the CC BY-SA 4.0 licence.
Available in 10 languages
via Wikidata sitelinks · CC0