TAF13

Name

TATA-box binding protein associated factor 13

Type

protein-coding

Aliases

MRT60, TAF(II)18, TAF2K, TAFII-18, TAFII18

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

TATA-box binding protein associated factor 13

Symbol

TAF13

Biotype

Protein coding

Organism

Homo sapiens

Location

1:109,062,489-109,076,014

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein TAF13 PDB 1bh8.png

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