tandospirone
Sign in to saveTandospirone, sold under the brand name Sediel, is an anxiolytic and antidepressant medication used in Japan and China, where it is marketed by Dainippon Sumitomo Pharma. It is a member of the azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone.
Research
295 papers- Tandospirone-Induced Rhabdomyolysis.Clinical neuropharmacology · 2018
- Tandospirone augments cisplatin treatment by lowering cholesterol and managing distress in NSCLC patients.NPJ digital medicine · 2025
- Tandospirone enhances the anti-myocardial fibrosis effect of valsartan in spontaneously hypertensive rats.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
- Tandospirone prevents anesthetic-induced respiratory depression through 5-HT(1A) receptor activation in rats.Scientific reports · 2025
- Clinical Efficacy of Tandospirone on Functional Dyspepsia Patients with Anxiety: A Randomized, Placebo-Controlled Study.Digestive diseases and sciences · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 383.232125
Show 6 more facts
- Commons category
- Tandospirone
- subject has role
- serotonin receptor agonists
- chemical formula
- C₂₁H₂₉N₅O₂
- isomeric SMILES
- C1C[C@H]2C[C@@H]1[C@H]3[C@@H]2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5
- canonical SMILES
- C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5
- physically interacts with
- 5-hydroxytryptamine receptor 1A
via Wikidata · CC0
~5 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Anxiety and depression
- Augmentation for depression
- Other uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- History
- Society and culture
- Name
- References
{{Drugbox | Verifiedfields = changed | verifiedrevid = 470477293 | image = Tandospirone.svg | image_class = skin-invert-image | width = 250 | alt =
| tradename = Sediel | Drugs.com = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral | class = Serotonin 5-HT1A receptor agonist | ATC_prefix = None | ATC_suffix =
Excerpted from Wikipedia’s “tandospirone” article, available under the CC BY-SA 4.0 licence.