TASP1
Sign in to saveAlso known as C20orf13, dJ585I14.2, taspase 1, SULEHS
Threonine aspartase 1 is an enzyme that in humans is encoded by the TASP1 gene.
In the Vinony graph
Vinony's link graph records 3 inbound references to TASP1, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Vinony links it to 5 Wikipedia language editions.
Gene data
TASP1- Name
- taspase 1
- Type
- protein-coding
- Position
- 13,387,216–13,639,109 (−)
- Aliases
- C20orf13, SULEHS, dJ585I14.2
- Ensembl
- ENSG00000089123
- RefSeq RNA
- NM_001323602.2, NM_001323603.2, NM_001323604.2, NM_017714.3, NR_136628.2
- RefSeq protein
- NP_001310531.1, NP_001310532.1, NP_001310533.1, NP_060184.2, XP_016883418.1
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
taspase 1
- Symbol
- TASP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:13,387,216-13,639,109
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein TASP1 PDB 2a8i.png
Show 7 more facts
- HomoloGene ID
- 9795
- genomic start
- 13246709
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55617
- genomic end
- 13638932
- chromosome
- human chromosome 20
- cytogenetic location
- 20p12.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Threonine aspartase 1 is an enzyme that in humans is encoded by the TASP1 gene.
== Function ==
Excerpted from Wikipedia’s “TASP1” article, available under the CC BY-SA 4.0 licence.