English
tauroursodeoxycholic acid
Sign in to saveAlso known as tauroursodeoxycholate, TUDA, TUDCA, 3alpha,7beta-dihydroxy-5beta-cholanoyltaurine, N-ursodeoxycholoyltaurine, 2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl) amino)ethanesulfonic acid, N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)taurine, Ursodeoxycholyltaurine
Ursodoxicoltaurine is the international nonproprietary name (INN) for the pharmaceutical form of tauroursodeoxycholic acid (TUDCA). It is also known as taurursodiol. Tauroursodeoxycholic acid is a naturally occurring hydrophilic bile acid which is the taurine conjugated form of ursodeoxycholic acid (UDCA). Humans have only trace amounts of tauroursodeoxycholic acid but bears have large amounts of tauroursodeoxycholic acid and ursodeoxycholic acid in their bile.
Research
1,329 papers- Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases.Translational neurodegeneration · 2022
- Tauroursodeoxycholic Acid Improves Nonalcoholic Fatty Liver Disease by Regulating Gut Microbiota and Bile Acid Metabolism.Journal of agricultural and food chemistry · 2024
- Tauroursodeoxycholic acid ameliorates renal injury induced by COL4A3 mutation.Kidney international · 2024
- Neuroprotective Effect of Tauroursodeoxycholic Acid (TUDCA) on In Vitro and In Vivo Models of Retinal Disorders: A Systematic Review.Current neuropharmacology · 2024
- Sodium Phenylbutyrate and Tauroursodeoxycholic Acid: A Story of Hope Turned to Disappointment in Amyotrophic Lateral Sclerosis Treatment.Clinical drug investigation · 2024
via PubMed
~8 min read
Encyclopedic overview
9 sectionsContents
- Synthesis
- Medical uses
- Cellular mechanisms
- Research
- Photoreceptor cells
- Choroidal neovascularization
- Synaptic connectivity
- Other diseases
- References
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477861058 | ImageFile=Tauroursodeoxycholic acid.svg | ImageSize=200 | IUPACName=2-(3α,7β-Dihydroxy-5β-cholan-24-amido)ethane-1-sulfonic acid | SystematicName=2-{(4R)-4-[(1R,3aS,3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido}ethane-1-sulfonic acid | OtherNames=Tauroursodeoxycholic acid; TUDCA; 3α,7β-Dihydroxy-5β-cholanoyltaurine; UR 906; Ursodeoxycholyltaurine; Taurursodiol |Section1= |Section2= |Section3= | Section6 = }}
Ursodoxicoltaurine is the international nonproprietary name (INN) for the pharmaceutical form of tauroursodeoxycholic acid (TUDCA). It is also known as taurursodiol. Tauroursodeoxycholic acid is a naturally occurring hydrophilic bile acid which is the taurine conjugated form of ursodeoxycholic acid (UDCA). Humans have only trace amounts of tauroursodeoxycholic acid but bears have large amounts of tauroursodeoxycholic acid and ursodeoxycholic acid in their bile.
Excerpted from Wikipedia’s “tauroursodeoxycholic acid” article, available under the CC BY-SA 4.0 licence.