chenodiol

Also known as CDCA, Chenix®, chenodeoxycholate, Chenodiol®, 7alpha-hydroxylithocholic acid, anthropodeoxycholic acid, chenic acid, gallodesoxycholic acid

chemical compound

Chemical data

Formula: C24H40O4
Molecular weight: 392.6 g/mol
IUPAC name: (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
InChIKey: RUDATBOHQWOJDD-BSWAIDMHSA-N
XLogP: 4.9
Polar surface area: 77.8 Å²
H-bond donors: 3
H-bond acceptors: 4
Formal charge: 0

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Research

6,653 papers

Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety.Annals of internal medicine · 1981
Current status of chenodeoxycholic acid (chenodiol) therapy of cholesterol gallstones.Seminars in liver disease · 1983
Chenodiol and gallstones.Annals of internal medicine · 1982
Chenodeoxycholic acid.Lancet (London, England) · 1978
Chenodiol for dissolving gallstones.The Medical letter on drugs and therapeutics · 1983

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Wikidata facts

Mass: 392.293

Show 5 more facts

chemical formula: C₂₄H₄₀O₄
canonical SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
isomeric SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
MCN code: 2918.19.22
Commons category: Chenodeoxycholic acid

Sources (7)

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