CYP7A1

Name

cytochrome P450 family 7 subfamily A member 1

Type

protein-coding

Position

58,490,174–58,500,164 (−)

Aliases

CP7A, CYP7, CYPVII

Ensembl

ENSG00000167910

RefSeq RNA

NM_000780.4

RefSeq protein

NP_000771.2

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010].

via MyGene.info

Gene · Ensembl

cytochrome P450 family 7 subfamily A member 1

Symbol

CYP7A1

Biotype

Protein coding

Organism

Homo sapiens

Location

8:58,490,174-58,500,164

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

PDB 3dax EBI.png

via Wikidata · CC0