CYP11B2
Sign in to saveAlso known as ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo
protein-coding gene in the species Homo sapiens
Gene data
CYP11B2- Name
- cytochrome P450 family 11 subfamily B member 2
- Type
- protein-coding
- Position
- 142,910,424–142,917,943 (−)
- Aliases
- ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo
- Ensembl
- ENSG00000179142
- RefSeq RNA
- NM_000498.3
- RefSeq protein
- NP_000489.3
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytochrome P450 family 11 subfamily B member 2
- Symbol
- CYP11B2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:142,910,424-142,917,943
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI