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GeneQ18040174· pop 5· linked from 155 articles

Also known as cytochrome P450 family 39 subfamily A member 1

CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1) also known as oxysterol 7-α-hydroxylase 2 is a protein that in humans is encoded by the CYP39A1 gene.

Gene data

CYP39A1
Name
cytochrome P450 family 39 subfamily A member 1
Type
protein-coding

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

via MyGene.info

Gene · Ensembl

cytochrome P450 family 39 subfamily A member 1

Symbol
CYP39A1
Biotype
Protein coding
Organism
Homo sapiens
Location
6:46,549,383-46,652,831
Strand
Reverse (−)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

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Encyclopedic overview

3 sections
Contents
  • References
  • External links
  • Further reading

CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1) also known as oxysterol 7-α-hydroxylase 2 is a protein that in humans is encoded by the CYP39A1 gene.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol.

Excerpted from Wikipedia’s “CYP39A1” article, available under the CC BY-SA 4.0 licence.

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