CYP3A43
Sign in to saveAlso known as cytochrome P450 family 3 subfamily A member 43
Cytochrome P450 3A43 is a protein that in humans is encoded by the CYP3A43 gene.
Gene data
CYP3A43- Name
- cytochrome P450 family 3 subfamily A member 43
- Type
- protein-coding
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
via MyGene.info
Gene · Ensembl
cytochrome P450 family 3 subfamily A member 43
- Symbol
- CYP3A43
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:99,827,922-99,867,801
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cytochrome P450 3A43 is a protein that in humans is encoded by the CYP3A43 gene.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.
Excerpted from Wikipedia’s “CYP3A43” article, available under the CC BY-SA 4.0 licence.