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thiazesim

Structure via PubChem · Public domain (PubChem)

EntityQ7800304· pop 6· linked from 290 articles

Also known as tiazesim

Tiazesim (), or thiazesim (, ), previously sold under the brand name Altinil, is a heterocyclic antidepressant related to the tricyclic antidepressants (TCAs) which, introduced in 1966 by Squibb Corporation (now Bristol-Myers Squibb), has since been discontinued and is no longer marketed.

Chemical data

Formula
C19H22N2OS
Molecular weight
326.5 g/mol
IUPAC name
5-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one
SMILES
CN(C)CCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CC=C3
InChIKey
QJJXOEFWXSQISU-UHFFFAOYSA-N
XLogP
3.1
Polar surface area
48.9 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
326.145
Show 2 more facts
canonical SMILES
CN(C)CCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CC=C3
chemical formula
C₁₉H₂₂N₂OS
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

Tiazesim (), or thiazesim (, ), previously sold under the brand name Altinil, is a heterocyclic antidepressant related to the tricyclic antidepressants (TCAs) which, introduced in 1966 by Squibb Corporation (now Bristol-Myers Squibb), has since been discontinued and is no longer marketed.

==See also== Diltiazem Tofenacin

Excerpted from Wikipedia’s “thiazesim” article, available under the CC BY-SA 4.0 licence.

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