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thiopropamine

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thiopropamine

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Also known as amthietamine

Thiopropamine, also known as 1-(2-thienyl)-2-aminopropane, is a stimulant drug of the arylalkylamine family. It is an analogue of amphetamine where the phenyl ring has been replaced by thiophene. It has similar stimulant effects to amphetamine but with around one third the potency. The N-methyl and thiophen-3-yl analogues are also known and are somewhat more potent, though still generally weaker than the corresponding amphetamines.

Chemical data

Formula
C7H11NS
Molecular weight
141.24 g/mol
IUPAC name
1-thiophen-2-ylpropan-2-amine

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

~1 min read

Encyclopedic overview

5 sections
Contents
  • Pharmacology
  • Chemistry
  • Derivatives
  • See also
  • References

Thiopropamine, also known as 1-(2-thienyl)-2-aminopropane, is a stimulant drug of the arylalkylamine family. It is an analogue of amphetamine where the phenyl ring has been replaced by thiophene. It has similar stimulant effects to amphetamine but with around one third the potency. The N-methyl and thiophen-3-yl analogues are also known and are somewhat more potent, though still generally weaker than the corresponding amphetamines.

==Pharmacology== Like amphetamine and most of its analogues, thiopropamine most likely is a norepinephrine–dopamine reuptake inhibitor and/or releasing agent.

Excerpted from Wikipedia’s “thiopropamine” article, available under the CC BY-SA 4.0 licence.

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